Midazolam in rabbits terminates dysrhythmias caused by intracerebroventricular ropivacaine
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چکیده
منابع مشابه
Not your regular high: cardiac dysrhythmias caused by loperamide.
OBJECTIVE Loperamide, a non-prescription anti-diarrheal agent, is a peripheral mu-opioid receptor agonist that is excluded from the blood-brain barrier by p-glycoprotein at therapeutic doses. Overdoses of loperamide penetrate the central nervous system (CNS), leading to abuse. We report cardiac conduction abnormalities and dysrhythmias after ingestion of a recreational supra-therapeutic dose of...
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Reovirus was isolated from commercial rabbit colonies in farms at KafrElsheikh and El-Gharbia Governorate with a history of neonatal hydrocephalus and blindness. The affected neonates exhibited hydrocephalus at age from 3-20 days with seasonal incidence at a late summer and early autumn (August, Sept. and Oct.). The gross lesions observed at necropsy were bulging of the skull, collapse of the c...
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BACKGROUND Ropivacaine is available for spinal or intrathecal use in humans, although data on neurotoxicity after spinal injection are not yet available. The authors experimentally determined the relationship between doses of intrathecal ropivacaine and spinal effects and local neurotoxic effects. METHODS Eighty rabbits equipped with an intrathecal lumbar catheter were studied. Sixty were ran...
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In parallel with improvements in understanding pain neurophysiology, many chemicals have recently been investigated for spinal anaesthesia and analgesia. However, studies discussing the effects of these drugs on neural tissue indicate that knowledge about some aspects of neurotoxicity is limited. Forty-nine New Zealand albino rabbits, weighing 2.2 +/- 0.2 kg, were randomly assigned to seven gro...
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Calcium channel blockers can get involved in pharmacological interactions when used concomitantly with other drugs. Previous reports indicate a differential influence of various general anesthetics on verapamil pharmacokinetics. A tendency of a faster transfer of verapamil from the central compartment to the tissue compartment was found to be associated with a slower drug return from the tissue...
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ژورنال
عنوان ژورنال: Journal of Zhejiang University SCIENCE B
سال: 2011
ISSN: 1673-1581,1862-1783
DOI: 10.1631/jzus.b1000337